Science
www.sciencemag.org
3 APRIL 2009
VOL 324, ISSUE 5923, PAGES 1-130
Sequencing and Analyses of All Known Human Rhinovirus Genomes Reveal Structure and Evolution Palmenberg AC, Spiro D, Kuzmickas R, Wang S, Djikeng A, Rathe JA, Fraser-Liggett CM, Liggett SB.
Science 3 April 2009: Vol. 324. no. 5923, pp. 55 - 59
DOI: 10.1126/science.1165557
Click on images below to see larger versions.
Legend
Journal Cover (Copyright © 2009): QuteMol-rendered image of human rhinovirus 3 (Protein Data Bank ID: 1rhi) illustrating virion topography. Red, blue, and yellow denote the three major surface capsid proteins; examples of RNA regional motifs are colored according to predicted base-pairing fidelity. Sequence diversity within the major surface proteins contributes to the wide range of immunogenic serotypes characteristic of the “common cold.” See page 55.
Image: H. Adam Steinberg (Archived) and Jean-Yves Sgro University of Wisconsin-Madison. Update: H. Adam Steinberg affiliations: artforscience | StoryForm Science | WID | MERI | linkedin
X-ray crystallography data: Zhao, R., Pevear, D.C., Kremer, M.J., Giranda, V.L., Kofron, J.A., Kuhn, R.J., Rossmann, M.G. (1996) Human rhinovirus 3 at 3.0 A resolution. Structure 4: 1205-1220
