The Journal of Allergy and Clinical Immunology
www.jacionline.org
Volume 125, Issue 6, Pages 1175-1476 (June 2010)
(Archived March 30, 2021)
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Journal Cover (Copyright © 2010): About the cover - On our cover this month, a QuteMol-rendered image of human rhinovirus 3 (pdbID: 1rhi) illustrates the virion topography. The surface depressions around the 5-fold symmetry axes contribute to receptor binding (ICAM-1). Higher regions on the capsid surfaces encode the immunogenic serotype. An example of an HRV RNA genome secondary structure is colored according to predicted base-pairing fidelity. This image highlights this month’s emphasis on viruses in asthma. In our Clinical Reviews series, David Jackson and Sebastian L. Johnston (p1178) discuss the role that viruse splay in asthma exacerbations. For our Mechanisms series, Ann C. Palmenberg et al. (p1190) provide an analysis of human rhinovirus genome sequences and the implications for future treatments and research. A Current Perspectives article by Peter D. Sly et al. (p 1202) reviews the latest evidence regarding whether viral infections early in life cause asthma. To find these and other articles relevant to this month’s theme, look for the red starburst icon in the Table of Contents. The components contained in this month’s cover were created by H. Adam Steinberg (Archived) and Jean-Yves Sgro, University of Wisconsin-Madison. Adapted for thecover by JDI, LLC. The Editors also wish to thank James Gern and Ann Palmenberg for their assistance. © 2010 American Academy of Allergy, Asthma & Immunology
Update: H. Adam Steinberg affiliations: artforscience | StoryForm Science | WID | MERI | linkedin
X-ray crystallography data: Zhao, R., Pevear, D.C., Kremer, M.J., Giranda, V.L., Kofron, J.A., Kuhn, R.J., Rossmann, M.G. (1996) Human rhinovirus 3 at 3.0 A resolution. Structure 4: 1205-1220
